Ranson’s Criteria Calculation


Ranson’s Criteria Calculation
1. WBC >16k (On Admission)
2. Age >55 years (On Admission)
3. Glucose >200 mg/dL (>11.1 mmol/L) (On Admission)
4. AST >250 (On Admission)
5. LDH >350 (On Admission)
6. Hct drop >10% from admission (48 Hours Into Admission)
7. BUN increase >5 mg/dL (>1.79 mmol/L) from admission (48 Hours Into Admission)
8. Ca <8 mg/dL (<2 mmol/L) within 48 hours (48 Hours Into Admission)
9. Arterial pO2 <60 mmHg within 48 hours (48 Hours Into Admission)
10. Base deficit (24 – HCO3) >4 mg/dL within 48 hours (48 Hours Into Admission)
11. Fluid needs >6 L within 48 hours (48 Hours Into Admission)

Welcome to the intriguing world of Ranson’s Criteria calculation. Just to tickle your funny bone, did you know what the pancreas and a secret agent have in common? They both operate undercover! Alright, enough humor, let’s get serious!

Ranson’s Criteria Calculation Formula

    Ranson's Criteria Score = (On admission: age > 55 years, WBC count > 16,000/mm3,
    blood glucose level > 200 mg/dL, serum LDH > 350 IU/L, serum AST > 250 U/100 mL) +
    (After 48 hours: Hematocrit fall > 10%, BUN increase > 5 mg/dL,
    arterial PO2 < 60 mm Hg, serum Calcium < 8 mg/dL, Base deficit > 4 mEq/L,
    estimated fluid sequestration > 6 L)

Ranson’s Criteria Categories

Category Score Interpretation
Mild 0-2 Low risk of severe disease
Moderate 3-4 Intermediate risk
Severe 5-6 High risk
Critical 7-8 Very high risk

Ranson’s Criteria Calculation Examples

Person Ranson’s Score Calculation Result
John Doe 3 (2 for age, 1 for WBC count) Moderate risk
Jane Doe 5 (3 for age, 2 for BUN increase) High risk

Calculation Methods

Method Advantages Disadvantages Accuracy
Ranson’s Criteria Established, widely used Can be complex High
Modified Glasgow Criteria Simpler Less established Moderate

Evolution of Ranson’s Criteria

Year Changes
1974 Initial criteria proposed
1980s Criteria revised and expanded
1990s Use of criteria becomes widespread

Limitations of Ranson’s Criteria

  1. Age Factor: May overestimate severity in elderly patients.
  2. Time Factor: Criteria must be recalculated after 48 hours to maintain accuracy.

Alternative Methods

Method Pros Cons
APACHE II More comprehensive More complex
BISAP Simpler, less invasive Less accurate

FAQs on Ranson’s Criteria

  1. What is Ranson’s Criteria? Answer: It’s a tool used to predict the severity and prognosis in pancreatitis.
  2. How is Ranson’s Criteria calculated? Answer: It involves adding certain risk factors to give an overall score.
  3. When should Ranson’s Criteria be calculated? Answer: It’s calculated both on admission and after 48 hours.
  4. How accurate is Ranson’s Criteria? Answer: It has high accuracy but can overestimate severity in elderly patients.
  5. What are the limitations of Ranson’s Criteria? Answer: The main limitations are the age factor and the need for recalculation after 48 hours.
  6. What are alternatives to Ranson’s Criteria? Answer: Alternatives include APACHE II and BISAP.
  7. What is a good score on Ranson’s Criteria? Answer: A lower score is better, indicating a lower risk of severe disease.
  8. Can Ranson’s Criteria predict mortality? Answer: Yes, it’s used to predict severity of pancreatitis, which can be linked to mortality.
  9. What does a high score on Ranson’s Criteria indicate? Answer: A high score indicates a high risk of severe disease.
  10. Who proposed Ranson’s Criteria? Answer: It was proposed by Dr. John Ranson in 1974.


  1. National Institute of Diabetes and Digestive and Kidney Diseases: Detailed information on pancreatitis.
  2. MedlinePlus: Comprehensive, patient-friendly information on pancreatitis and its management.